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Bounds must be chosen without inspecting confidential patient values. They define clipping domains and therefore enter the sensitivity argument.

Usage

pmx_bounds(
  time,
  endpoints,
  amt = NULL,
  rate = NULL,
  covariates = NULL,
  limit = NULL
)

Arguments

time

Bounds for actual study time.

endpoints

Named list of DV bounds, one pair per endpoint declaration.

amt, rate

Optional amount and rate bounds.

covariates

Named list of numeric covariate bounds.

limit

Named list of censoring-limit bounds by endpoint.

Value

A public pmx_bounds configuration object.